Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge.
BackgroundMany ruminant diseases of viral aetiology can be effectively prevented using appropriate vaccination measures.For diseases such as Rift Valley fever (RVF) the long inter-epizootic periods make routine vaccination programs unfeasible.Coupling RVF prophylaxis with seasonal vaccination programmes by means of multivalent vaccine platforms wou